UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

Filed by the Registrant  ☒                Filed by a Party other than the Registrant  ☐

Check the appropriate box:

AVITA MEDICAL, INC.

(Name of Registrant as Specified in Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than Registrant)

Payment of Filing Fee (Check the appropriate box):

Aggregate number of securities to which transaction applies:

Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the filing fee is calculated and state how it was determined):

Proposed maximum aggregate value of transaction:

Total fee paid:

Amount Previously Paid:

Form, Schedule, or Registration Statement No.:

Filing Party:

Date Filed:

To the Security Holders of

AVITA MEDICAL, INC.

Re: 20212022 Annual Meeting of Stockholders

Dear Security Holders:Holders,

You are cordially invited to attend AVITA Medical, Inc.’s (the “Company”) 20212022 Annual Meeting of Stockholders which is being held on December 14, 202112, 2022, at 1:2:00 p.m.pm Pacific Standard Time (being December 15, 202113, 2022, at 8:00am9:00 am Australian Eastern Daylight Time). This year’s

The Company’s 2022 Annual Meeting will beis being held by way of a completely virtual meeting conducted via live webcast. You will be able to attend the Annual Meetingwebcast with an online by visiting http://voting platform at meetnow.global/MTJNRZR. HoldersMRZS45W.

All holders of the Company’s shares of common stock (“Common Stock”) and CHESS Depositary Interests (“CDIs”) are invited to attend the 2022 Annual Meeting either in person or virtually.

Holders of Common Stock will be able to vote their shares electronically atCommon Stock via the Annual Meetingonline voting platform and submit questions. Holders of the Company’s CHESS Depositary Interests (“CDIs”)CDIs will not be able to vote electronically atduring the Annual Meeting or submit questions,via the online voting platform but will be able to attend as guests.ask questions virtually. Holders of CDIs can, however, direct CHESS Depositary Nominees Pty Ltd (“CDN”) to vote the Common Stock underlying their CDIs. Further details regarding how holders of Common Stock and CDIs can vote are set out in this Proxy Statement.

The formal Notice of the Annual Meeting follows on the next page. Details regarding how to attend the meeting online and the business to be conducted at the Annual Meeting are more fully described in the accompanying Notice of Annual Meeting and Proxy Statement.

AllThe Company hopes that all holders of the Company’s Common Stock and CDIs are invitedwill be able to virtually attend the Annual Meeting and the Company hopes you will be able to virtually attend.virtually. Whether or not you expect to virtually attend the Annual Meeting, you are urged to vote or submit your proxy card or CDI Voting Instruction Form as soon as possible after you have finished reading the Notice of Annual Meeting and Proxy Statement so that your shares of Common Stock (or shares of Common Stock underlying your CDIs) can be voted at the Annual Meeting in accordance with your instructions.

You may vote your shares of Common Stock (or direct CDN to vote for you if you hold your shares of Common Stock in the form of CDIs) by following the instructions on the enclosed proxy card or CDI Voting Instruction Form (as applicable). If you hold your shares of Common Stock through an account with a brokerage firm, bank, or other nominee, please follow the instructions you receive from them as to how to vote your shares.shares of Common Stock.

Please vote, sign, and return the enclosed proxy card or CDI Voting Instruction Form (as applicable) as soon as possible, whether or not you plan to attend the Annual Meeting. Your vote is important.

NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

TO BE HELD ON DECEMBER 14, 202112, 2022 AT 2:00 PM (PACIFIC STANDARD TIME) (BEING

DECEMBER 15, 202113, 2022 AT 9:00 AM (AUSTRALIAN EASTERN DAYLIGHT TIME (“AEDT”))

To the Stockholders of

AVITA MEDICAL, INC.

NOTICE IS HEREBY GIVEN that the Annual Meeting of Stockholders of AVITA Medical, Inc. (the “Company”), a Delaware corporation, will be held on Tuesday, December 14, 202112, 2022, at 1:2:00 p.m.pm Pacific Standard Time (being Wednesday, December 15, 202113, 2022, at 8:9:00 a.m. AEDT)am Australian Eastern Daylight Time (“AEDT”)),by way of a virtual meeting conducted via live webcast with an online voting platform at http://meetnow.global/MTJNRZR,MRZS45W for the following purposes:

The Board of Directors has fixed 5:00 p.m. on October 26, 202119, 2022 (Pacific Daylight Time) (being 11:00 a.m. on October 27, 202120, 2022 (AEDT)) as the record date for the Annual Meeting and only record holders of shares of the Company’s common stock at that time will be entitled to receive notice of, and to vote at, the Annual Meeting of Stockholders or any adjournment or adjournments thereof and only holdersthereof. Holders of CDIs of the Company at that time will be entitled to receive notice of, and to attend (but not vote at), the Annual Meeting or any adjournment or adjournments thereof. This Proxy Statement and the accompanying proxy and CDI Voting Instruction Form will be mailed on or about November 11, 2021.October 25, 2022.

Valencia, CA                 November     , 20212022

IMPORTANT

THE 20212022 ANNUAL MEETING WILL BE HELD VIRTUALLY AND NO ONE WILL PHYSICALLY ATTEND THE MEETING.BY WAY OF A VIRTUAL MEETING CONDUCTED VIA LIVE WEBCAST. IT IS REQUESTED THAT YOU INDICATE YOUR VOTE ON THE ISSUESRESOLUTIONS INCLUDED ON THE ENCLOSED PROXY CARD OR CDI VOTING INSTRUCTION FORM (AS APPLICABLE) AND DATE, SIGN AND MAIL IT IN THE ENCLOSED SELF-ADDRESSED ENVELOPE WHICH REQUIRES NO POSTAGE IF MAILED IN THE UNITED STATES (IN RELATION TO THE PROXY CARD) AND WHICH REQUIRES NO POSTAGE IF MAILED IN AUSTRALIA (IN RELATION TO THE CDI VOTING INSTRUCTION FORM). HOLDERS OF THE COMPANY’S COMMON STOCK MAY ALSO VOTE AT THE MEETING VIRTUALLY BY THE ONLINE VOTING PLATFORM. HOLDERS OF CDIS WILL NOT BE ABLE TO VOTE DURING THE ANNUAL MEETING VIA THE ONLINE VOTING PLATFORM AND CAN VOTE ONLY BY COMPLETING THE CDI VOTING INSTRUCTION FORM.

IMPORTANT NOTICE REGARDING THE AVAILABILITY OF PROXY MATERIALS FOR THE

STOCKHOLDER MEETING TO BE HELD ON DECEMBER 14, 2021:12, 2022, AT 2:00 PM (PACIFIC STANDARD TIME) (BEING DECEMBER 13, 2022, AT 9:00 AM (AEDT)): The Notice of Annual Meeting of Stockholders, Proxy Statement and the Annual Report to Stockholders are available on the following website: www.avitamedical.com/2021proxyhttp://www.edocumentview.com/RCEL

TABLE OF CONTENTS

AVITA MEDICAL, INC.

28159 Avenue Stanford, Suite 220

Valencia, CA 91355

PROXY STATEMENT

for

ANNUAL MEETING OF STOCKHOLDERS

to be held on December 14, 202112, 2022, at 1:2:00 pm (Pacific Standard Time)

(being December 15, 202113, 2022, at 8:9:00 am (Australian Eastern Daylight Time (“AEDT”))

SOLICITATION OF PROXY

The accompanying proxy is solicited on behalf of the board of directors (the “Board of Directors”) of AVITA Medical, Inc., a Delaware corporation (“AVITA” or the “Company”), for use at the annual meeting of stockholders of the Company (the “Annual Meeting”) to be held at 1:2:00 p.m.pm Pacific Standard Time on December 14, 202112, 2022 (being 8:9:00 am AEDT on December 15, 2021)13, 2022) by way of a virtual meeting conducted via live webcast with an online voting platform at http://www.meetingcenter.io/.meetnow.global/MRZS45. This Proxy Statement contains information about the matters to be considered at the meeting or any adjournments or postponements of the meeting. In addition to mail, proxies may be solicited by personal interview, telephone or telegraph by our officers and regular employees, without additional compensation. We will bear the cost of solicitation of proxies. Brokerage houses, banks and other custodians, nominees and fiduciaries will be reimbursed for out-of-pocket and reasonable expenses incurred in forwarding proxies and proxy statements.

As announced in December 2021, the Company changed its fiscal year from June 30 to December 31. As a result of this change, the Company reported a six-month Transition Period. The Transition Period is from July 1, 2021 to December 31, 2021. As a result of the change from fiscal year to calendar year, the proposals contained in the Annual Meeting will, where applicable, relate to the period ending December 31, 2022.

The Board of Directors has set 5:00 p.m.pm Pacific Daylight Time on October 26, 202119, 2022 (being 11:00 am AEDT on October 27, 2021)20 2022) as the record date (the “Record Date”) to determine those holders of record of Common Stock, par value US$0.0001, who are entitled to notice of, and to vote at (either in-person or virtually), the Annual Meeting and those holders of CHESS Depositary Interests (“CDIs”) (representing the underlying shares of Common Stock) who are entitled to notice of, and to attend (but not vote at), the Annual Meeting. Each share of Common Stock (including the underlying shares of Common Stock represented by CDIs, with five CDIs representing one share of Common Stock) entitles its owner to one vote. On the Record Date, there were                  24,925,118 shares of Common Stock outstanding (including the underlying shares of Common Stock represented by CDIs). On or about November 11, 2021,October 25, 2022, this Proxy Statement, the proxy card (the “Proxy Card” or “Proxy”) and the CDI Voting Instruction Form (as applicable) are being mailed to stockholders and CDI holders of record as of the Record Date.

IMPORTANT: To ensure that your shares of Common Stock are represented at the Annual Meeting, please vote your shares of Common Stock (or, for CDI holders, direct CHESS Depositary Nominees Pty Ltd (“CDN”) to vote your CDIs) via marking, signing, dating, and returning the enclosed Proxy Card or CDI Voting Instruction Form (as applicable) to the address specified. If you attend the Annual Meeting virtually, you may choose to vote via the online platform at http://meetnow.global/MTJNRZRMRZS45W (as applicable) if you qualify to do so, even if you have previously voted your shares of Common Stock, except that CDI holders may only instruct CDN to vote on their behalf by completing and signing the CDI Voting Instruction Form and may not vote virtually atduring the Annual Meeting.

1Meeting via the online platform.

ABOUT THE MEETING

What is being considered at the meeting?

You will be voting on the following:

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every five CDIs that you own. CDN or its custodian is considered the shareholder of record for the purposes of voting at our Annual Meeting. As the beneficial owner, you have the right to direct CDN or its custodian as to how to vote the shares in your account. As a beneficial owner, you are invited to attend the Annual Meeting. However, because you are not a stockholder of record, if you personally want to vote the shares of Common Stock underlying your CDIs at the Annual Meeting, you must inform CDN via your CDI Voting Instruction Form that you wish to nominate yourself (or another person, including the Chair of the Annual Meeting) to be appointed as CDN’s proxy for the purposes of virtually attending and voting at the Annual Meeting.

Under the rules governing CDIs, CDN is not permitted to vote on your behalf on any matter to be considered at the Annual Meeting unless you specifically instruct CDN how to vote. We encourage you to communicate your voting decisions to CDN in advance of the Annual Meeting to ensure that your vote will be counted by completing the enclosed CDI Voting Instruction Form and returning it to the address specified on that form.

How many votes must be present to hold the meeting?

Your shares are counted as present at the meeting if you attend the meeting virtually and vote in personvia the online platform at meetnow.global/MRZS45W (in the case of holders of Common Stock) or if you properly return a Proxy or CDI Voting Instruction Form by mail. To conduct our meeting, a majority of the combined voting power of our Common Stockcapital stock as of October 26, 202119, 2022 (United States) must be present at the meeting. This is referred to as a quorum. On October 26, 2021,19, 2022 (United States), there were 24,925,118[Insert Quantity] outstanding shares of Common Stock (including Common Stock represented by CDIs) entitled to vote.

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Can I change my mind after I submit my Proxy or CDI Voting Instruction Form?

Yes, if you hold shares of Common Stock, you may change your mind at any time before a vote is taken at the meeting. You can do this by (1) signing another Proxy with a later date and submitting it in the same manner as the prior Proxy was submitted; (2) if you hold your shares in your name, voting again at the meeting;meeting via the online voting platform; or (3) if you hold your shares in street name, arranging with your broker to vote your shares at the Annual Meeting.

If you are a holder of CDIs and you direct CDN to vote by completing the CDI Voting Instruction Form, you may revoke those directions by delivering to Computershare Australia a written notice of revocation bearing a later date than the CDI Voting Instruction Form previously sent, which notice must be received by Computershare Australia by no later than 7:9:00 pmam (AEDT) on December 9, 2021.7, 2022 (being 2.00 pm (Pacific Standard Time) / 5.00 pm (Eastern Standard Time) on December 6, 2022.

Will my shares or CDIs be voted if I do not provide my Proxy or CDI Voting Instruction Form?

If you hold your shares of Common Stock directly in your own name, they will not be voted if you do not provide a Proxy unless you personally vote at the meeting via the online voting platform. Your shares of Common Stock may be voted under certain circumstances if they are held in the name of a brokerage firm. Brokerage firms generally have the authority to vote a customer’s unvoted shares on certain “routine” matters, including approval of the appointment of independent public accountants. When a brokerage firm votes its customer’s unvoted shares, these shares are counted for the purposes of establishing a quorum. At the Annual Meeting, these shares will be counted as voted by the brokerage firm in relation to the approval of the appointment of our independent public accountants.

If you hold CDIs, they will not be voted if you do not provide a completed CDI Voting Instruction Form to Computershare Australia by the relevant cut-off date, being 9:00 am (AEDT) on December 7, 2022 (being 2.00 pm (Pacific Standard Time) / 5.00 pm (Eastern Standard Time) on December 6, 2022).

Since the proposal to amend our Certificate of Incorporation and Amended and Restated Bylaws (“Bylaws”) to reduce the quorum requirement for stockholder meetings requires the affirmative vote of a majority of all outstanding shares of Common Stock, whether or not voted at the Annual Meeting, unvoted shares of Common Stock (including the underlying shares of Common Stock represented by CDIs) will have the effect of being a vote against that proposal.

What if I return my Proxy Card or CDI Voting Instruction Form but do not include voting instructions?

Proxies that are signed and returned but do not include voting instructions will be voted FOR the election of the nominated directors, FOR the ratification of the appointment of our independent public accountants, FOR the approvalamendment of the amendmentsCompany’s Certificate of Incorporation and Bylaws to reduce the Company’s Amended and Restated Bylaws, FOR the ratification of the

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What does it mean if I receive more than one Proxy Card or CDI Voting Instruction Form?

If you receive more than one printed set of proxy materials, it means that you hold Common Stock or CDIs registered in more than one account. To ensure that all of your Common Stock or CDIs are voted, please submit proxies or CDI Voting Instruction Forms for all of your shares of Common Stock or CDIs (as applicable).

If possible, we recommend that you contact your broker and/or our transfer agent to consolidate as many accounts as possible under the same name and address. Our transfer agent in the United States is Computershare Limited. Computershare Limited’s telephone number is 800-736-3001. Our transfer agent in Australia is Computershare Australia. Computershare Australia’s telephone number is +61 39415 4000 (overseas(for overseas callers) or 1300 850 505 (for calls within Australia).

Will my shares or CDIs be voted if I do not provide my Proxy or CDI Voting Instruction Form?

If you hold your shares of Common Stock directly in your own name, they will not be voted if you do not provide a Proxy unless you personally vote at the meeting. Your shares may be voted under certain circumstances if they are held in the name of a brokerage firm. Brokerage firms generally have the authority to vote a customer’s unvoted shares on certain “routine” matters, including approval of the appointment of independent public accountants. When a brokerage firm votes its customer’s unvoted shares, these shares are counted for the purposes of establishing a quorum. At our meeting, these shares will be counted as voted by the brokerage firm in the approval of the appointment of our independent public accountants.

If you hold CDIs, they will not be voted if you do not provide a completed CDI Voting Instruction Form to Computershare Australia by the relevant cut-off date, being December 9, 2021 at 7:00 pm AEDT.

What vote is required to approve each item?

The affirmative vote of a plurality of the votes cast at the Annual Meeting is required for the approval of the election of directors and the affirmative vote of a majority of the votes cast is required for (i) the ratification of the appointment of our independent public accountants; (ii) the ratification of the Company’s issue of 3,214,250 shares of Common Stock; (iii) the approval of the amendments to the Company’s Amended and Restated Bylaws; (iv) the approval of the increase to the non-executive directors maximum aggregate annual cash fee pool; (v) the approval of the grant of options and restricted stock units and options to each non-executive director; and (vi)(iii) the approval of the grant options to the Company’s President and CEO Approval of optionsthe amendment of our Certificate of Incorporation and restrictedour Bylaws to reduce the quorum requirement for stockholder meetings requires the majority of the voting power of the stock unitsof the Company entitled to Dr. Michael Perry.vote thereon to vote in favor of the proposal. The advisory vote to approve executive compensation will be approved, on a non-binding, advisory basis, on the affirmative vote of a majority of the votes cast at the Annual Meeting.

Where can I find the voting results of the Annual Meeting?

The preliminary voting results will be announced at the Annual Meeting. In accordance with the requirements of ASX Listing Rule 3.13.2, the Company will disclose to ASX the voting results of the Annual Meeting immediately after the meeting. The Company will also report the results on a current report on Form 8-K filed with the U.S. Securities and Exchange Commission.

Who pays for solicitation of proxies?

5The Company is paying the cost of soliciting proxies and will reimburse brokerage firms and other custodians, nominees and fiduciaries for their reasonable out-of-pocket and reasonable expenses for sending proxy materials to stockholders and obtaining their votes. In addition to soliciting the proxies by mail, certain of our directors, officers and regular employees, without compensation, may solicit proxies personally or by telephone, facsimile and email. In connection with the foregoing, the Company has retained Okapi Partners LLC to solicit proxies on its behalf for the Annual Meeting. We have agreed to pay to Okapi Partners, LLC a fee of approximately $25,000. In Australia, the Company has engaged Georgeson Shareholder Communications Australia Pty Ltd. to solicit proxies from holders of CDIs. We have agreed to pay Georgeson Shareholder Communications Australia Pty Ltd. a fee of approximately $48,000.

How can I submit a proposal for the 2023 annual meeting of stockholders?

Requirements for Stockholder Proposals to Be Considered for Inclusion in the Company’s Proxy Materials. Stockholder proposals, including a nomination for election to the Board of Directors, to be considered for inclusion in the proxy statement and form of proxy relating to the 2023 annual meeting of stockholders must be received by June 26, 2023. In addition, all proposals will need to comply with Rule 14a-8 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), which lists the requirements for the inclusion of stockholder proposals in company-sponsored proxy materials. Stockholder proposals must be delivered to the Company’s Secretary at 28159 Avenue Stanford, Suite 220, Valencia, California, 91355.

Requirements for Stockholder Proposals to Be Brought Before the 2023 Annual Meeting of Stockholders. Notice of any director nomination or other proposal that you intend to present at the 2023 annual meeting of stockholders, but do not intend to have included in the proxy statement and form of proxy relating to the 2023 annual meeting of stockholders, must be delivered to the Company’s Secretary at 28159 Avenue Stanford, Suite 220, Valencia, California, 91355 not later than the close of business on June 26, 2023 or a reasonable time before the Company begins to print and send its proxy materials. In addition, your notice must set forth the information required by our Bylaws with respect to each director nomination or other proposal that you intend to present at the 2023 annual meeting of stockholders.

Universal Proxy Requirements. In addition to satisfying the foregoing requirements under our Bylaws, to comply with the universal proxy rules, stockholders who intend to solicit proxies in support of director nominees other than the company’s nominees must provide notice that sets forth the information required by Rule 14a-19 under the Exchange Act no later than October 12, 2023, or a reasonable time before the Company begins to print and send its proxy materials.

Do we currently have, or do we intend to submit for stockholder approval, any anti-takeover device?

Our Certificate of Incorporation, Amended and Restated Bylaws (“Bylaws”) and other corporate documents do not have any provisions that contain material anti-takeover aspects. We have no plans or proposals to submit any other amendments to our Certificate of Incorporation or Bylaws, or other measures in the future, that have anti-takeover effects.

Could emerging developments regarding the coronavirus — or COVID-19 — affect our ability to hold an in-person annual meeting?

We have been monitoringare continuing to monitor the impact of the COVID-19 situation,pandemic on our employees, customers, and on the markets in which we operate. The ultimate extent of the impact of the COVID-19 pandemic on us, including the rapidly spreading Delta variant, closelydiscovery and have determinedspread of existing and future contagious variants to COVID-19, remains highly uncertain and will depend on future developments and factors that holdingcontinue to evolve. These factors, among others include the widespread vaccination of populations including recently approved booster regimens, especially in the U.S. and improvements in treatments and therapeutics for those with an in-person annualCOVID-19, meeting would pose a risk to the health and safetywhich are outside of our stockholders, employees,control, and directors, or otherwise be counter to public health directives.could exist for an extended period of time even after the pandemic might end. Further imposition of quarantines, shelter-in-place and similar government orders which are outside of our control could impact the manner in which we hold our meeting virtually. Accordingly, the Company has decidedchosen to instead hold a virtual Annual Meeting.Meeting so that security holders can attend the meeting via live webcast with an online voting platform at meetnow.global/MRZS45W.

To attend and participate in the virtual Annual Meeting virtually, securityholders of record will need to access the live audio webcast of the meeting. To do so, please visit https://meetnow.global/MTJNRZRMRZS45W and use the 16-digit Control Number provided in the Notice of Annual Meeting to log in to this website, and beneficial owners of shares held in street name will need to follow the instructions provided by the broker, bank or other nominee that holds their shares. Holders of the Company’s CDIs may attend the Annual Meeting virtually by logging into meetnow.global/MRZS45W as a visitor / guest to access the live audio webcast of the meeting. We encourage security holders to log in to this website and access the webcast before the virtual Annual Meeting’s start time.

6time if they are attending the Annual Meeting virtually.

Proposal No. 1

ELECTION OF DIRECTORS

Our Board of Directors has one class of directors, with each director elected annually for a term of one year in accordance with our Bylaws. Unless specified to be voted otherwise, the persons named in the accompanying Proxy will vote for the election of the following persons as directors, all of whom are presently members of the Board of Directors, to hold office for the terms set forth below or until their respective successors have been elected and qualified. The nominees have consented to serve as directors if elected.

Dr. Michael Perry, a non-executive director of the Company and the Company’s former President and Chief Executive Officer, will not be standing for re-election at the Annual Meeting and will therefore cease to be a director of the Company with effect from the date of the Annual Meeting.

The Board of Directors recommends that you elect the nominees identified below.

Business Experience

Louis Panaccio has served as Non-Executive Chairman of the Board of Directors since July 2014. Mr. Panaccio is a successful healthcare businessman with extensive experience leading companies from concept to commercialization. Mr. Panaccio possesses more than 30 years of executive leadership experience in healthcare services and life sciences, including more than 20 years of board-level experience. Mr. Panaccio is currently a Non-Executive Director of ASX50 company and one of the world’s largest medical diagnostics companies, Sonic Healthcare Limited, where he has served since 2005. In addition, Mr. Panaccio is Non-Executive Director of Unison Housing Limited, was Non-Executive Chairman of Genera Biosystems Limited until June 2019 and was a Non-Executive Director of Rhythm Biosciences Limited, a publicly listed (ASX) development-stage medical diagnostics company. We believe Mr. Panaccio is qualified to serve on our Board of Directors based on his extensive experience in the healthcare services and life sciences sectors and his experience in serving on boards.

Dr.James Corbett Michael Perry was appointed Executive Directoras President and Chief Executive Officer in June 2017. Prior to this appointment, Dr. PerryCEO of the Company effective as of September 28, 2022. Mr Corbett served as a Non-Executive Director commencingfrom July 2021 to September 28, 2022. He has approximately 40 years of leadership experience in February 2013. From 2016 to 2017,the medical device field, most recently as CEO of CathWorks Ltd., a software-based medical technology company. Mr. Corbett has extensive global commercial and operating experience, serving as an expatriate General Manager of Baxter Japan and later as General Manager and President of Scimed Life Systems Inc. and Boston Scientific International, respectively. During his career he has served as Senior Vice President and Chief Scientific Officer of Global Business Development and Licensing for Novartis AG. From 2014 to 2016, Dr. Perry served as Chief Scientific Officer of Novartis’ Cell and Gene Therapy Unit, and from 2012 to 2014 he served as Vice President and Global Head of Stem Cell Therapy for Novartis Pharmaceuticals Corp, a U.S. affiliate of Switzerland-based Novartis AG. Dr. Perry previously served as the Global Head of R&D at Baxter Healthcare, President and CEO of Cell & Gene Therapy at Novartis affiliates Systemixthree publicly listed companies: Microtherapeutics Inc (MTIX), ev3 Inc (evvv) and Alphatec Spine (ATEC). Mr. Corbett has also led two privately funded companies as CEO: Home Diagnostics Inc. and Genetic Therapy, Inc., VP Regulatory Affairs at Sandoz Pharmaceuticals Corp., DirectorVertos Medical. Mr. Corbett has extensive capital markets and governance experience from both public and private environments. Mr. Corbett holds a Bachelor of Regulatory Affairs at Schering-Plough Corporation, and Chairman, CEO or CMO at several early-stage biotech companies. He also previously served as a Venture Partner with Bay City Capital, LLC, a life science investment firm managing venture capital funds, basedScience in San Francisco California. Dr. Perry serves as a DirectorBusiness Administration from the University of Arrowhead Pharmaceuticals, a public (NASDAQ) development stage company focused on medicines

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Jeremy Curnock Cook has served as a Non-Executive Director since October 2012. He is a veteran in the life sciences/healthcare industry and has been actively supporting the commercialization of healthcare innovations and helping entrepreneurs build their international businesses over the past 45 years. Founder and Managing Director of BioScience Managers, Jeremy brings his decades of international experience to our Board of Directors. Over his career, Mr. Curnock Cook has successfully managed in excess of US $1billion in equity investments. He launched the first dedicated biotechnology fund for the Australian market and is a former head of the life science private equity team at Rothschild Asset Management, an early pioneer and significant investor in the sector. In his early career he founded the International Biochemicals Group which he successfully sold to Royal Dutch Shell. He co-created a European-focused seed fund with Johnson & Johnson and built the International Biotechnology Trust. He has served on more than 40 boards of directors in the life science sector in the UK, Europe, USA, Canada, Japan and Australia. In addition to serving on our Board of Directors, Jeremy currently serves on the following boards: Sea DragonInternational BioScience Managers Ltd appointed October 2012, RexMarch 2000, Bioscience Managers Pty Ltd appointed January 2003, REX Bionics Pty Ltd appointed February 2012, Armata PharmaceuticalsSea Dragon appointed July 1995, SummatiX PtyOctober 2012, Smart Matrix Ltd appointed July 2017,February 2013, Adherium Ltd appointed April 2015, JLCC Ltd appointed December 2019, Bioscience Managers UK Ltd appointed August 2017, Bioscience Managers PtyCriL appointed November 2020, and Humanetix Ltd appointed January 2003, International BioScience Managers Ltd appointed March 2000, Arecor Ltd appointed October 2018, Smart Matrix Ltd appointed February 2013, Gen InCode appointed July 2020 and CRiL appointed November 2020.September 2021. We believe Mr. Curnock Cook is qualified to serve on our Board of Directors based on his extensive experience in the life sciences sector.

Louis Drapeau has served as a Non-Executive Director since January 2016. Mr. Drapeau has considerable expertise in both the biotech sector and with the financial reporting and other requirements of U.S. public companies. From March 2011 until May 2019, Mr. Drapeau served as an Independent Director at AmpliPhi Biosciences Corporation, Inc., a public (NYSE) clinical-stage biotechnology company focused on the development of bacteriophage-based therapies for the treatment of antibiotic-resistant bacterial infections. Mr. Drapeau has held senior positions with Insite Vision Inc., Nektar Therapeutics and BioMarin Pharmaceutical, Inc., and served as an Audit Partner at Arthur Andersen LLP. Mr. Drapeau was previously an Independent Director at Bio-Rad Laboratories, a public (NYSE) company manufacturing products for the life science research and clinical diagnostics markets, and InterMune, Inc., a public (NASDAQ) commercial-stage biotech company. He has an MBA from Stanford University. We believe Mr. Drapeau is qualified to serve on our Board of Directors based on his experience with financial reporting and other requirements of U.S. public companies, and considerable expertise in the biotech sector.

Professor Suzanne Crowe AO has served as a Non-Executive Director since January 2016. Australian-based, she is a physician-scientist with expertise in supporting companies with their medical and scientific strategies. A Fellow of the Australian Institute of Company Directors, she is currently a Non-Executive Director of St Vincent’s Health Australia Ltd, the country’s largest not-for-profit health and aged care provider, and Non-Executive Director of Sonic Healthcare Ltd, a large global medical diagnostic company. She was appointed Emeritus Professor, Monash University, Melbourne in 2020. After 35 years at both, she has recently retired from the Burnet Institute, having served as Associate Director Clinical Research, and the university-affiliated Alfred Hospital Melbourne, where she held the appointment of Senior Specialist Physician in Infectious Diseases. She was appointed as Officer of the Order of Australia in June 2020 in recognition of her distinguished services to health, clinical governance, biomedical research, and education. She has medical and MD degrees from Monash University, an internal medicine specialist qualification in Infectious Diseases from the Royal Australasian College of Physicians, and a Diploma in Medical Laboratory Technology from the Royal Melbourne Institute of Technology. We believe Professor Crowe is qualified to serve on our Board of Directors based on her technical experience and extensive expertise in supporting companies with their medical and scientific strategies.

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Committee Table

On September 8, 2021, the Board appointed Jan Stern Reed and James Corbett to each serve as an Independent Director on the Company’s Audit Committee and its Compensation Committee, effective September 8, 2021. Additionally, on September 8, 2021 the Board appointed Jan Stern Reed to serve as an Independent Director on the Nominations & Corporate Governance Committee of the Board, effective September 8, 2021. Ms. Reed and Mr. Corbett’s appointments to the above stated committees were madepursuant to the Board’s determination that Ms. Reed and Mr. Corbett satisfy all applicable requirements to serve on the above stated committees, includingwithout limitation, the applicable requirements of the ASX Listing Rules and the Securities Exchange Act of 1934, as amended. Jeremy Curnock Cook stepped down from his role as a member of the Audit Committee on September 8, 2021, being the same day that Jan Stern Reed and James Corbett were appointed to the Audit Committee.

The current committees of the Board and their respective members are as follows:

Each of these committees operates under a written charter and reports regularly to the Board. A copy of each of these committee charters which have been amended as of August 10, 2022 is available in the “Investors” section of our website under the heading “Corporate Governance” at ir.avitamedical.com, and copies may also be obtained by request through the “Contact” heading at the same website address.

Audit Committee

NASDAQ Marketplace Rules require us to establish an audit committee comprised of at least three members, each of whom is financially literate and satisfies the respective “independence” requirements of the SEC and NASDAQ and one of whom has accounting or related financial management expertise at senior levels within a company. In addition, the 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations recommend that we have an audit committee comprised of at least three members, all of whom are non-executive directors and a majority of whom are “independent” directors, and which is chaired by an independent director who is not the chair of the board.

We have a separately designated standing Audit Committee established in accordance with Section 3(a)(58)(A) of the Exchange Act. Our Audit Committee assists our Board of Directors in overseeing the accounting and financial reporting processes of our company and audits of our financial statements, including the integrity of our financial statements, compliance with legal and regulatory requirements, our registered public accounting firm’s qualifications and independence, and registered public accounting firm, and such other duties as may be directed by our Board of Directors. The Audit Committee is also required to assess risk management in conjunction with the board.

Our Audit Committee currently consists of three board members, each of whom satisfies the “independence” requirements of the SEC, NASDAQ Marketplace Rules, and the 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations. Our Audit Committee is currently composed of Lou Panaccio, Jan Stern Reed and Jeremy Curnock Cook. Each qualifies as an “independent director” within the meaning of NASDAQ Marketplace Rules and the 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations. Mr. Curnock Cook is the interim chair of the Audit Committee (being an independent director who is not the chair of the board) and was appointed on September 28, 2022. Our Board of Directors has determined that Mr. Curnock Cook is an “audit committee financial expert,” as defined in item 407(d)(5)(ii) of Regulations S-K. The Audit Committee meets at least two times per year. See below for a summary of attendance during the transition period ended December 31, 2021, and during the six months thereafter from January 1, 2022 to June 30, 2022.

Compensation Committee

Our Board of Directors has established a Compensation Committee, which is comprised of independent directors, within the meaning of NASDAQ Marketplace Rules and also the 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations. The Compensation Committee is comprised solely of non-executive directors and is also chaired by an independent director in accordance with the 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations. The Compensation Committee is responsible for reviewing the salary, incentives and other benefits of our directors, senior executive officers and employees, and for making recommendations on such matters for approval by our Board of Directors. The Compensation Committee is also responsible for overseeing and advising our Board of Directors with regard to the adoption of policies that govern our compensation programs. Suzanne Crowe, Jeremy Curnock Cook, and Jan Stern Reed are the current members of the Compensation Committee and each qualifies as an “independent director” within the meaning of NASDAQ Marketplace Rules and the 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations. Professor Crowe is the chair of this committee (being an independent director who is not the chair of the board).

The number of meetings the Compensation Committee held during the transition period ended December 31, 2021, and during the six months thereafter from January 1, 2022 to June 30, 2022 and the number of meetings attended by each Director is as follows:

Nominating & Corporate Governance Committee

Our Board of Directors has established a Nominating and Corporate Governance Committee (the “Nominating Committee”). The 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations recommends that a Nominating Committee should have at least three members, a majority of whom are independent directors and should also be chaired by an independent director. Suzanne Crowe, Jan Stern Reed and Jeremy Curnock Cook are the current members of the Nominating Committee and each qualifies as an “independent director” within the meaning of NASDAQ Marketplace Rules and the 4^th Edition of the ASX’s Corporate Governance Principles and Recommendations. Professor Crowe is the chair of this committee (being an independent director). The Nominating Committee is responsible for identifying individuals qualified to become members of our Board of Directors, recommending nominees for election at stockholder meetings or to fill vacancies that arise on our Board of Directors, and recommending qualified and experienced directors to serve on the committees of our Board of Directors. In addition, the Nominating Committee is responsible for leading the Board of Directors through the completion of a self-evaluation of the Board, its committees, and individual directors.

The number of meetings the Nominating Committee held during the transition period ended December 31, 2021, and during the six months thereafter from January 1, 2022, to June 30, 2022, and the number of meetings attended by each Director is as follows:

Process for Nominating Potential Director Candidates

The Nominating Committee is responsible for identifying and evaluating potential director candidates and recommending qualified candidates for election by the stockholders consistent with criteria approved by the Board. Nominees for director are selected by the Nominating Committee on the basis of their (i) economic, academic, financial, and other expertise, skills, knowledge, and achievements useful to the oversight of the Company’s business; (ii) integrity, demonstrated sound business judgment, and high moral and ethical character; (iii) diversity of viewpoints, backgrounds, experiences, and other demographics; (iv) business or other relevant professional experience; (v) capacity and desire to represent the balanced, best interests of the Company and its stockholders as a whole and not primarily a special interest group or constituency; (vi) ability and willingness to devote time to the affairs and success of the Company and in fulfilling the responsibilities of a director; and (vii) the extent to which the interplay of the candidate’s expertise, skills, knowledge, and experience with that of other Board members will build a Board that is effective, collegial, and responsive to the needs of the Company.

The Nominating Committee does not have a formal diversity policy with respect to the Board, but it reviews the background and qualifications of each nominee to determine such nominee’s experience, competence, and character and assesses such nominee’s potential contribution to the Board of Directors, taking into account the then-existing composition of the Board of Directors and such other factors as the Nominating Committee deems appropriate. The Board should collectively possess skills, industry, and other knowledge and expertise, and business and other experience useful for the effective oversight of the Company’s business. The Nominating Committee believes that the business experience of its directors has been, and continues to be, critical to the Company’s development and plan of operation.

The Nominating Committee values the input of stockholders in identifying director candidates. Accordingly, although the Nominating Committee does not have a specific policy with regard to the consideration of candidates recommended by stockholders, the Nominating Committee considers recommendations for Board candidates submitted by stockholders using substantially the same criteria it applies to recommendations from the Nominating Committee, directors and members of management. Any such nominations should be submitted to the Nominating Committee in line with the instructions provided under the caption “How can I submit a proposal for the 2023 annual meeting of stockholders?” above and in compliance with other specific procedural requirements set forth in the Bylaws.

Board Diversity Matrix

conjunction particularly with the Audit Committee) monitors and receives advice on areas of operational and financial risk and considers strategies for appropriate risk management arrangements. Specific areas of risk which are regularly considered at Board meetings include foreign currency, performance of activities, human resources, acceptance by regulatory authorities of the Company’s products, markets, manufacturing, the environment, statutory compliance, and continuous disclosure obligations. Additional areas of focus for the Board of Directors include, but are not limited to:

More broadly, risks are considered in virtually every business decision and process and as part of the Company’s overall business strategy. While the Board of Directors has the ultimate oversight responsibility for the Company’s risk management policies and processes, the committees of the Board of Directors also have responsibility for risk oversight. As noted above, our Audit Committee assists the Board of Directors to meet its oversight responsibilities in respect of various areas of risk for the Company including risks associated with our financial statements and financial reporting, internal control structure, risk management procedures and the internal (as applicable) and external audit function as well as mergers and acquisitions, credit and liquidity, and business conduct compliance. Our Compensation Committee considers the risks associated with our compensation policies and practices with respect to both executive compensation and employee compensation. Our NominationsNominating and Corporate Governance Committee oversees risks associated with our overall governance practices and the leadership structure of the Board of Directors. Our Board of Directors stays informed of each committee’s risk oversight and other activities via regular reports of the committee chairs to the full Board of Directors. Our Board of Directors’ role in risk oversight is consistent with our leadership structure, with the Chief Executive Officer and other members of senior management having responsibility for assessing and managing the Company’s risk exposure, and the Board of Directors and committees providing oversight in connection with those efforts.

Stockholder and Interested Party Communications with Directors

10Stockholders may communicate with the Board of Directors, members of particular committees, or individual directors by sending a letter to such persons care of our Chief Executive Officer at our principal executive offices. The Chief Executive Officer has the authority to disregard any inappropriate communications or to take other appropriate actions with respect to any inappropriate communications. If deemed an appropriate communication, the Chief Executive Officer will submit the correspondence to the Chairman of the Board or to the committee or specific director to whom the correspondence is directed. All such communications must be accompanied by a statement of the type and amount of our securities that the person holds; any special interest, meaning an interest that is not derived from the proponent’s capacity as a stockholder, of the person in the subject matter of the communication; and the address, telephone number and e-mail address, if any, of the person submitting the communication.

Proposal No. 2

RATIFICATION OF APPOINTMENT OF INDEPENDENT REGISTERED

PUBLIC ACCOUNTING FIRM

The Board of Directors, on the recommendation of the Audit Committee, has appointed Grant Thornton LLP to serve as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2022.

Stockholders previously approved the ratification of the appointment of Grant Thornton LLP to serve as the Company’s independent registered public accounting firm at the 2021 annual meeting for the fiscal year ending June 30, 2022 (being prior to the Company’s change in fiscal year end to 31 December). This proposal seeks stockholder approval for the ratification of the appointment of Grant Thornton LLP to serve as the Company’s registered public accounting firm for the fiscal year ending December 31, 2022.

The Board of Directors recommends that you vote to ratify such appointment.

Representatives of Grant Thornton LLP are expected to be available at the virtually held Annual Meeting of stockholders with the opportunity to make a statement if they desire to do so and will be available to respond to appropriate questions.

Fees

The aggregate fees billed to us by Grant Thornton LLP for services rendered for each of the transition period ended December 31, 2021, and the fiscal year ended June 30, 2021, are set forth in the table below (in US dollars):

Vote Required

Ratification of the appointment of Grant Thornton LLP requires a number of “FOR” votes that is a majority of the votes cast by the Company’s stockholders present in person or represented by proxy at the Annual Meeting and entitled to vote on the Proposal, with abstentions counting as votes against the Proposal.

The Board of Directors recommends a vote “FOR” the ratification of the appointment of Grant Thornton.Thornton LLP.

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REPORT OF THE AUDIT COMMITTEE

The Audit Committee assists our Board in its oversight of our financial reporting process. All three members*members of the Audit Committee qualify as independent directors under NASDAQ listing standards for public companies and the independence requirements of Rule 10A-3 promulgated under the Securities Exchange Act of 1934, as amended (“Exchange Act”) and the Board has determined that one is qualified as an audit committee financial expert within the meaning of Item 407(d)(5) of Regulation S-K, promulgated under the Exchange Act. All three members* of the Audit Committee are also considered to be independent for the purposes of the ASX Listing Rules and the ASX Corporate Governance Council’s Corporate Governance Principles and Recommendations (4^th Edition). The Audit Committee’s charter can be viewed online on our website at https://ir.avitamedical.com/corporate-governance.

In fulfilling its duties, the Audit Committee reviewed and discussed the audited financial statements contained in the Company’s Annual Report on Form 10-K10-KT for the fiscaltransition year ended June 30,July 1, 2021, to December 31, 2021 with management and the independent auditor, Grant Thornton LLP. Management is responsible for the financial statements and the reporting process, including the systems for internal control over financial reporting. The independent auditor is responsible for performing an independent audit of the Company’s financial statements in accordance with accounting principles generally accepted in the United States, and for expressing an opinion on these financial statements based on the audit.

The Audit Committee met with the independent auditor with and without management present and discussed those matters required to be discussed by the applicable requirements of the Public Company Accounting Oversight Board and the U.S. Securities and Exchange Commission. The Audit Committee has also received the written disclosures and the letter from the independent auditor required by the applicable requirements of the Public Company Accounting Oversight Board regarding the independent auditor’s communications with the Audit Committee concerning independence and discussed with the independent auditor its independence.

Based on the above reviews and discussions, the Audit Committee recommended to our Board, and our Board approved, that the audited financial statements be included in the Company’s Annual Report on Form 10-K10-KT for the fiscaltransition year ended June 30,July 1, 2021, to December 31, 2021, for filing with the U.S. Securities and Exchange Commission. Beginning January 1, 2022, the Company is now a calendar year reporter.

Submitted by the Audit Committee*:Committee:

Louis Drapeau,James Corbett^*, Chair of the Audit Committee

Jeremy Curnock Cook

LouLouis Panaccio

Jan Stern Reed

Date: October [XX][Insert Date]

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS

Principal Stockholders and Management

The following table provides certain information regarding the ownership of our common stock (including our CDIs), 2021as of September 1, 2022, by each person or group of affiliated persons known to us to be the beneficial owner of more than 5% of our common stock (including our CDIs); each of our named executive officers; each of our directors; and all of our executive officers and directors as a group. The table also sets out the names of all persons (of which the Company is aware) who have disclosed pursuant to the Corporations Act 2001 (Cth) that they are “substantial shareholders” of the Company and carry 5% or more of the voting rights attached to the issued securities of the Company.

Unless otherwise indicated in the table or the related notes, the address for each person named in the table is c/o AVITA Medical, Inc., 28159 Avenue Stanford, Suite 220, Valencia, CA 91355.

Information about our Executive Officers

James Corbett is discussed above under Proposal 1: Election of Directors.

Michael Holder was appointed Chief Financial Officer in March 2021. Mr. Holder is a seasoned executive with more than 25 years of experience serving in senior financial, executive management and board roles with leading companies in the medtech, biotech and pharma industries. Most recently, Mr. Holder served as Chief Financial Officer of ImmuneCyte Inc., a global clinical stage biopharmaceutical company with innovative cell and gene immune-oncology therapeutics. Between 2017 and 2018, Mr. Holder served as CEO and Portfolio Manager of Carolina Longevity Institute, a global investment company focused on medtech, biotech and pharma investments in the healthspan and human longevity sectors. From 2005 to 2017, Mr. Holder was CEO, CFO, and Chairman of the Board of Organ Transport Systems, Inc. a medical device company in the organ transplantation industry. From 2000 to 2004, Mr. Holder was VP Sales, Operations and Finance; Chief Financial Officer of Premier Sourcing Partners, the information and medical technology subsidiary of Premier Inc. Prior to that, Mr. Holder was CFO of BeaconEye Inc., a publicly traded medtech company; Vice President of Heartland Capital Partners, the Sam Walton family controlled private equity fund; and Principal in the Corporate Development Group of AMR Corporation, a former Fortune 500 transportation and information technology company. Mr. Holder holds a Master of Business Administration from the Wharton School of Business at the University of Pennsylvania and a Bachelor of Science in Business Administration from the Kenan-Flagler Business School at the University of North Carolina at Chapel Hill.

Kathy McGee was appointed Chief Operating Officer in December 2020. She brings more than 25 years of biopharmaceutical and life sciences experience to AVITA Medical, most recently serving as President of CnA Consulting Group, which focuses on providing specialized consulting services to the life sciences industry. Prior to CnA Consulting, Ms. McGee was the Vice President of West Coast Operations at Shire Pharmaceuticals Regenerative Medicine Division, formerly Advanced BioHealing, where she was a part of the leadership team responsible for manufacturing operations, strategic planning, capital expansion, and real estate. At Advanced BioHealing, Ms. McGee served as the Senior Vice President of Operations and General Manager, with responsibility for the company’s manufacturing operations in La Jolla, CA. She has also held senior operations leadership roles at Smith and Nephew and Advanced Tissue Sciences. She earned her Bachelor of Science in Chemistry and Mathematics from University College Galway Ireland, and holds a Master’s degree in Business and Management from Webster University.

Dr. Michael Perry has served as a Non-Executive Director since September 28, 2022. Prior to this appointment, Dr Perry served as Non-Executive Director commencing in February 2013 until he was appointed Executive Director and Chief Executive Officer from June 2017 to September 2022. From 2016 to 2017, he served as Senior Vice President and Chief Scientific Officer of Global Business Development and Licensing for Novartis AG. From 2014 to 2016, Dr. Perry served as Chief Scientific Officer of Novartis’ Cell and Gene Therapy Unit, and from 2012 to 2014 he served as Vice President and Global Head of Stem Cell Therapy for Novartis Pharmaceuticals Corp, a U.S. affiliate of Switzerland-based Novartis AG. Dr. Perry previously served as the Global Head of R&D at Baxter Healthcare, President and CEO of Cell & Gene Therapy at Novartis affiliates Systemix Inc. and Genetic Therapy, Inc., VP Regulatory Affairs at Sandoz Pharmaceuticals Corp., Director of Regulatory Affairs at Schering-Plough Corporation, and Chairman, CEO or CMO at several early-stage biotech companies. He also previously served as a Venture Partner with Bay City Capital, LLC, a life science investment firm managing venture capital funds, based in San Francisco California. Dr. Perry serves as a Director of Arrowhead Pharmaceuticals, a public (NASDAQ) development stage company focused on medicines employing RNA interference technology.

COMPENSATION AND OTHER INFORMATION CONCERNING OUR EXECUTIVE OFFICERS AND DIRECTORS

Executive Compensation

Summary Compensation Table

The following table sets forth for our named executive officers the following information for the transition period ended December 31, 2021, and the fiscal year ended June 30, 2021 (in US dollars).

Employment Contracts

The following table outlines the specified terms of the relevant employment contracts for the named executive officers of the Company. For compensation information of named executives refer to the table above.

Compensation Principles

The Compensation Committee has a formal Compensation Governance Framework which, at the core, consists of a Compensation Committee Charter (the “Charter”). The Charter outlines the responsibilities and duties of the members, sets forth the frequency of meetings and establishes and reviews the overall compensation philosophy of the Company. The Compensation Committee reviews and approves the executive compensation program for the Chief Executive Officer and other executive officers and makes appropriate recommendations to the Board of Directors.

Compensation Committee

The Compensation Committee approves or makes recommendations to our Board of Directors on decisions concerning compensation of the executive management team and Board of Directors on a periodic basis to ensure that it is consistent with our short-term and long-term goals. The Compensation Committee assess the appropriateness of the nature and amount of compensation of our executives by reference to relevant employment market conditions with the overall objective of ensuring maximum stakeholder benefit from the recruitment and retention of a high-quality board and executive team.

Additionally, the Compensation Committee is responsible for evaluating the performance of the Company’s key senior executives. Our Chief Executive Officer and other members of management regularly discuss our compensation issues with Compensation Committee members. Subject to Compensation Committee review, modification and approval, our Chief Executive Officer typically makes recommendations regarding bonuses and equity incentive awards for the other members of the executive management team. The Compensation Committee establishes all bonus and equity incentive awards for all executive members of the management team.

Resignation, Retirement, Termination for Cause, or Resignation without Good Reason Arrangements

The Company does not have any agreements or plans in place for the named executive officers that would provide additional compensation in connection with a resignation, retirement, termination for cause, or resignation without good reason.

Potential Payments upon Involuntary Termination, Resignation without Good Reason or Change-In-Control

The employment agreements provide for the following severance payments upon termination by us without cause or by the employee for good reason (as defined in the particular employment agreement): (i) payment of the employee’s then-current base salary for a period of nine months (in the case of COO and CFO) or twelve months (in the case of the CEO), following termination; (ii) a pro-rated target bonus for the period during which the employee was employed in the year of termination; and (iii) continued coverage under our group health and benefits plan consistent with the term of the base salary; and (iv) immediate acceleration of unvested stock options. Further, in the case of the Chief Executive Officer, if his employment terminates as a result of disability or death, he or his representative will be entitled to receive: (i) a lump sum payment equal to 12 months of the employee’s then-current base salary, (ii) any unpaid vacation, and (iii) any unpaid expense reimbursements due and owing. Payment in each case is subject to the employee’s, or representative’s execution of a release.

Outstanding Equity Awards at Fiscal Year End

The following table presents information regarding outstanding equity awards held by our named executive officers as of December 31, 2021 (in US dollars).

Proposal No. 3

APPROVAL OF AMENDMENTS TO THEAMENDMENT OF COMPANY’S CERTIFICATE OF INCORPORATION AND AMENDED AND RESTATED BYLAWS

Background TO REDUCE THE QUORUM REQUIREMENT FOR STOCKHOLDER MEETINGS

Proposal No. 3 seeks the approval from the Company’sof stockholders to an amendment to our Certificate of proposed amendmentsIncorporation (the “Certificate”) and an amendment to the Company’sour Amended and Restated Bylaws (“Bylaws”(the “Bylaws”) for the purpose of reducing the quorum requirement for the Company’s stockholder meetings. The Board has determined that it is in the Company’s and our stockholders’ best interests to amend the Certificate (the “Certificate Amendment”) and the Bylaws (the “Bylaws Amendment”) to reduce the quorum requirement for stockholder meetings from a majority of the outstanding voting securities of the Company (the “Current Quorum”) to one-third (33 1/3%) of the outstanding voting securities of the Company (the “Proposed Quorum”). The Board has adopted and declared advisable, the Certificate Amendment and the Bylaws Amendment, both of which amendments are necessary in order to implement the Proposed Quorum, subject to stockholder approval.

The Company is proposing to amend its Bylaws by inserting a new Section 7.10 (as set out below) that will give the Company the right to sell on behalf of a CDI holder the CDIs held by that CDI holder where the holding constitutes less than a marketable parcel of CDIs for the purposestexts of the ASX Listing Rulesproposed Certificate Amendment and Bylaws Amendment are included as Annexes A and B to this Proxy Statement.

Background

A quorum is the ASX Settlement Operating Rules.

Section 7.6minimum number of stockholders who must be present in person or by proxy at a stockholders meeting in order for that meeting to be validly held. It is a requirement under Delaware law that a company specify its quorum for its stockholder meetings by defining the proportion of the voting power that constitutes a quorum in its articles of incorporation or bylaws.

Our Certificate and our Bylaws providesprovide that the Bylaws may be amended by either the Board of Directors or the stockholders.

The Company is seeking to have this amendment to the Bylaws approved by stockholders. If this Proposal No. 3 is approved, the amendments to the Bylaws will take effect from December 14, 2021 (Pacific Standard Time).

Reasonscurrent quorum for the proposed amendments to the Bylaws

The Company has a large number of CDI holders on its register that hold less than a “marketable parcel” of CDIs. A marketable parcel is a CDI holding worth at least A$500. As at October 18, 2021, 5,737 CDI holders held less than a marketable parcel of CDIs. For a CDI holder that holds less than a marketable parcelmeeting of the Company’s CDIs, it may be difficult and/or expensive for them to sell those CDIs. It is also expensive and inefficient for the Company to maintain these small holdings given there are share registry fees and other administrative costs associated with maintaining such small holdings on the Company’s CDI register.

Our Board of Directors may, if it deems it appropriate to do so and if our Bylaws permit it, elect to implement a small holdings sale facility in relation to CDI holders that hold less than a marketable parcel of CDIs (“Sale Facility”) at the relevant time. Such a facility would, if implemented by the Company, provide a process pursuant to which the CDI holdings of CDI holders that hold less than a marketable parcel of CDIs could be compulsorily sold on their behalf by the Company (unless the holder gives notice to the Company that it does not wish its CDIs to be sold) without the CDI holder having to pay brokerage or other fees on the sale as such fees would be borne by the Company or the purchaser of the CDIs. The CDI holders would, however, still be responsible for any tax payable in connection with the sale of their CDIs and if a Sale Facility was to be implemented in the future it is recommended that the relevant CDI holders seek their own advice in relation to the implications for them of participating in a Sale Facility.

In order to implement a Sale Facility, the ASX Listing Rules require that a company’s constitution or bylaws must provide for certain matters that are set out in ASX Listing Rule 15.13. The Company’s Bylaws do not currently provide for the matters required by ASX Listing Rule 15.13.

Therefore, the Company is seeking the approval of stockholders under this Proposal No. 3 to amend its Bylaws to include the matters required by ASX Listing Rule 15.13. These matters will be set out in the proposed new Section 7.10 of the Bylaws. If approved, the new Section 7.10 of the Bylaws will allow the Company to implement a Sale Facility pursuant to which the Company can compulsorily sell the securities of a CDI holder who holds less than a marketable parcel of CDIs provided certain conditions are met (which include allowing the holders of less than a marketable parcel of CDIs a minimum 6-week period in which to opt-out of the automatic sale process, should they not wish to have their small holding sold on their behalf). The proceeds of the sale of

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the originally scheduled meeting dates for both our 2020 Annual Meeting and our 2021 Annual Meeting, which in both instances resulted in us adjourning the respective meeting for approximately one week to issueallow us to solicit further equity securities without stockholder approval overproxies and CDI Voting Instruction Forms from our stockholders in order to reach the 12-month period fromCurrent Quorum and validly hold the respective annual meeting. At both the 2020 Annual Meeting and 2021 Annual Meeting, only approximately 35% of CDI holders voted by submitting their CDI Voting Instructions Forms prior to the date of issuethe respective meeting.

The adjournments of our 2020 Annual Meeting and 2021 Annual Meeting due to the Current Quorum not being met resulted in disruption to the Company’s business and also the incurrence of significant additional costs, including additional payments to our share registries, virtual meeting hosts and our proxy solicitors.

Reasons for the Certificate Amendment and Bylaws Amendment

As a result of the shares of common stock underabove, the Offering.

ASX Listing Rule 7.4 sets out an exception to ASX Listing Rule 7.1. Under ASX Listing Rule 7.4, whereBoard has formed the view that a companyreduction in general meeting ratifies a previous issue of securities (made withoutthe Company’s quorum for any future stockholder approval under ASX Listing Rule 7.1), those securities will be excludedmeetings from the calculation ofCurrent Quorum to the number of securities that can be issued byProposed Quorum, and the company in any 12-month period within the 15% limit set out in ASX Listing Rule 7.1.

By ratifying the issue of the 3,214,250 shares of common stock that were issued under the Offering, such issue will be excluded from the calculation of the number of securities that can be issued by the Company in the 12-month period from the date of issue of the shares of common stock under the Offering for the purposes of ASX Listing Rule 7.1, thereby providing the Company with flexibilityCertificate Amendment and Bylaws Amendment to issue further securities during the 12-month period from the date of issue of the shares of common stock under the Offering without the requirement to obtain prior stockholder approval, if the Board of Directors considers itmake this change, is in the best interests of the Company and its stockholders, to do so.

Information required under ASX Listing Rule 7.5

Forbecause the purposesadoption of ASX Listing Rules 7.4the Proposed Quorum by making the Certificate Amendment and 7.5, the following information is provided:Bylaws Amendment:

and aligned with U.S. compensation practices. Alignment with U.S. compensation practices has become increasingly important following the Company’s redomiciliation from Australia to the U.S., its predominant focus on U.S. markets for its FDA approved RECELL^® product, and its completion of a U.S. institutional investor-based NASDAQ stock market public offering earlier this year (see Proposal No. 4). For the review, Compensia developed a peer group of 20 US-based public companies of similar size, industry, revenue, and market cap, using a rules-based approach.

Compensia provided the Company with recommendations in relation to non-executive director fees against competitive market data and confirmed to the Company that, in its view, the increase in the maximum aggregate annual cash fee pool from which all of the non-executive directors may be paid to US$750,000 is reasonable and “at market”. The Board of Director’s total cost of governance on an annualized basis if the proposed aggregate annual cash fee pool is increased to US$750,000 and the NED Securities proposed to be issued under Proposal No.’s 6 – 10 and 12 are approved (i.e. excluding those grants proposed to be made to Mr. Corbett and Ms. Reed in recognition of their appointment as non-executive directors of the Company under Proposal No’s 11 and 13) would be less than the 50^th percentile of peer group data set out in Compensia’s analysis.

If this Proposal No.5 is passed, the maximum aggregate annual cash fee pool from which non-executive directors may be paid for their services as members of the Board of Directors will be US$750,000. If this Proposal No.5 is not passed, the amount will remain at US$600,000.

Securities issued to non-executive directors under ASX Listing Rule 10.11 or 10.14

ASX Listing Rule 10.17 requires that the Company provide details of any securities issued to a non-executive director under ASX Listing Rule 10.11 or 10.14 with stockholder approval at any time within the preceding three years.

The Company confirms that no securities have been issued by the Company to any non-executive director under ASX Listing Rule 10.11 or 10.14 with stockholder approval within the past three years. If, however, Proposal No’s 64 – 13 (inclusive) are approved, restricted stock units and options in the Company (as applicable) will be issued to the Company’s non-executive directors under ASX Listing Rule 10.11 on the terms set out in this Proxy Statement in respect of those Proposals.

The Company’s predecessor, AVITA Medical Pty Limited, obtained approval at the annual general meeting of its shareholders on November 29, 2016 to issue a number of shares in AVITA Medical Pty Limited over the following three years (being the 2017, 2018 and 2019 financial years) under its employee share plan to each of its non-executive directors, namely Mr. Louis Panaccio, Mr. Jeremy Curnock Cook, Mr. Louis Drapeau, Professor Suzanne Crowe (who are also non-executive directors of the Company), Mr. Damien McDonald (who has since resigned as a non-executive director of the Company) and Dr. Michael Perry (who at the time was a non-executive director of AVITA Medical Pty Limited, but is now an executive director of the Company) in exchange for all or part of the directors’ fees otherwise payable to them. That approval was obtained for the purposes of section 195(4) and section 208 of the Corporations Act 2001 (Cth) and ASX Listing Rule 10.14 and for all other purposes.

Within the last three years, shares in AVITA Medical Pty Limited were issued to the non-executive directors during 2019 pursuant to that approval. The below table sets out those ordinary shares in AVITA Medical Pty Limited that were issued to non-executive directors in 2019. No other securities in AVITA Medical Pty Limited have been issued to non-executive directors under ASX Listing Rule 10.14 in the last three years. As a result of the redomiciliation of the Avita Group from Australia to the United States, the below mentioned securities were exchanged for equivalent securities in the Company in accordance with the relevant exchange ratios detailed in AVITA Medical Pty Limited’s Scheme Booklet dated 11 May 2020 (being 1:100). The current interests of each of the directors of the Company have been disclosed to ASX and are available on ASX’s website (www.asx.com.au).

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Table 1: Initial awardsNED Securities proposed to newbe granted

Set out below are details of the NED Securities proposed to be granted to the non-executive directors if approved under Proposal No’s 4 – 7.

Table 2: 2021 awards to non-executive directors

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Calculation of the number of NED Securities to be issued or transferred a sharegranted

As noted above, it is proposed that, subject to stockholder approval at the Annual Meeting, each of the above mentioned non-executive directors will be granted RSUs to acquire shares of common stock equal in value to US$87,500(as at the date of the Company for each RSU on a futuregrant) and options to acquire shares of common stock equal in value to US$37,500 (as at the date (after the vesting of the grant).

The number of NED Securities to be granted to each relevant RSU entitlement).non-executive directors on the date of grant will be determined in accordance with the following formulae:

In respect of the RSUs:    R = A / B

where:

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In respect of the options:     O = X / Y

where:

Table 2: Illustrative examples (only) of how the number of RSUs and options will be calculated

Set out below are example calculations, for illustrative purposes (only), of how the number of NED Securities to be granted to a non-executive director will be calculated by applying the above formulae. These examples have been calculated by reference to the lowest closing price of the Company’s common stock and highest closing price of the Company’s common stock on NASDAQ over the 6-month period to August 31, 2022.

It is important that stockholders note that the below calculations are examples only and the number of NED Securities that will actually be granted will be calculated on the basis of on the closing price of the Company’s shares of common stock on NASDAQ on the date that the relevant non-executive directors are granted their NED Securities, which will be the date of the Annual Meeting or shortly thereafter. As a result, the number of NED Securities actually granted to each relevant non-executive director may vary materially from the examples set out below.

Example 1 – Lowest closing price on NASDAQ over 6-month period to August 31, 2022:

If, by way of example, a non-executive director had been granted their NED Securities on the date of the lowest closing price of the Company’s common stock on NASDAQ over the 6-month period to August 31, 2022) the number of NED Securities to be granted to that non-executive director would, by applying the abovementioned formulae as follows:

RSUs

Options

O = 8,152 RSUs to acquire 8,152 shares of common stock (or 40,760 CDIs if so elected) (being the result of dividing X by Y)

Example 2 – Highest closing price on NASDAQ over 6-month period to August 31, 2022:

If, by way of example, a non-executive director had been granted their NED Securities (the date of the highest closing price of the Company’s common stock on NASDAQ over the 6-month period to August 31, 2022, the number of NED Securities to be granted to that non-executive director would, by applying the abovementioned formulae, be as follows:

RSUs

R = 8,278 RSUs to acquire 8,278 shares of common stock (or 41, 390 CDIs if so elected) (being the result of dividing A by B)

Options

O = 3,547 RSUs to acquire 3,547 shares of common stock (or 17,735 CDIs if so elected) (being the result of dividing X by Y)

If stockholder approval is obtained, the NED Securities proposed to be granted to each relevant non-executive director will be granted under and subject to the terms and conditions of a template RSU agreement (in respect of the RSUs) and a template option agreement (in respect of the options) and a template RSU agreement (in respect of the RSUs) to be entered into between the relevant non-executive director and the Company (“NED Security Agreements”), the terms of which are summarized below.

Each of Proposal No’s 64 – 137 (inclusive) are separate Proposals to be considered by stockholders independently. In addition, Proposal No’s 64 – 137 (inclusive) are not interdependent Proposals, meaning that the approval of one Proposal will not impact the outcome of another Proposal (e.g., if Proposal No.6No.4 is not approved, this does not impact the ability of Proposal No.7No.5 to be approved). Accordingly, if only some of Proposal No’s 64 – 137 are approved by stockholders, those Proposals that are approved will remain valid even if certain of Proposal No’s 64 – 137 are not approved by stockholders.

Those non-executive directors who have the grant of NED Securities to them approved will be entitled to be granted those NED Securities whereas those non-executive directors who do not have the grant of NED Securities to them approved will not be entitled to be granted those NED Securities.

ASX Listing Rule 10.11

The requirement to seek stockholder approval for the grant of the NED Securities contained in ASX Listing Rule 10.11. ASX Listing Rule 10.11 provides that a company must not, subject to specified exceptions, issue or agree to issue any equity securities to a related party, which includes a director, without stockholder approval. If stockholder approval in relation to Proposal No’s 64 – 137 is received, approval is not required under ASX Listing Rule 7.1 and the subsequent issue of the shares of common stock (or CDIs) the subject of the options and RSUs will not be counted towards the Company’s 15% placement capacity restriction set out in ASX Listing Rule 7.1.

Reasons for the grant of NED Securities

The Board has approved the proposed grant of the NED Securities in order to promote ownership in the Company by the non-executive directors and to align their interests with stockholders by linking part of their compensation to the long-term success of the Company and its financial performance. The provision of the NED Securities is an essential component of compensation for U.S. based non-executive directors of NASDAQ listed companies and the Board believes that the grant of the NED Securities should assist the Company in retaining members of the Board of Directors in an increasingly competitive environment for the recruitment and retention of non-executive directors.

As noted above, the Board is of the view that the grant of the NED Securities to the above mentioned non-executive directors is a reasonable and appropriate method to provide cost effective remuneration to thethose non-executive directors as the non-cash form of this remuneration will allow the Company to spend a greater proportion of its cash reserves on its operations than it would if alternative cash forms of remuneration were required to be givenprovided to thethose non-executive directors instead of the NED Securities.

Material terms of the NED Security Agreements

In addition to the number,value, vesting schedules and other terms of the RSUs and options and RSUs summarizednoted in the tables above, the following is a summary of other material terms of the NED Security Agreements. This summary is qualified in its entirety by reference to the template NED Security Agreements, copies of which are attached as Exhibits to this Proxy Statement.

Option Agreements

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If a non-executive director ceases to be a director of the Company prior to the relevant expiration date of the option due to being terminated for cause, the option will terminate and be forfeited immediately upon the director’s termination, and the director will be prohibited from exercising any portion (including any vested portion) of the option on or after the date of termination. If the director’s service as a non-executive director of the Company is suspended pending an investigation as to whether the director will be terminated for cause, all of the director’s rights under the option, including the right to exercise any vested options, will be suspended during the investigation period.

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RSU Agreements